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重組小鼠的堿性纖維生長因子Murine FGF-basic
更新時間：2013-06-19
點擊次數：1529
| Synonyms : | Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin | ||||||||||||||||||||
| Description : | FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant murine FGF-basic is a 16.2 kDa protein consisting of 145 amino acid residues. | ||||||||||||||||||||
| Catalog #: | 450-33 | ||||||||||||||||||||
| Source : | E.coli | ||||||||||||||||||||
| Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted FGF-basic is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. | ||||||||||||||||||||
| Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. | ||||||||||||||||||||
| Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg （1EU/μg）. | ||||||||||||||||||||
| Biological Activity : | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is < 0.1ng/ml corresponding to a specific activity of > 1 x 107 units/mg. | ||||||||||||||||||||
| AA Sequence : | MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS | ||||||||||||||||||||
| Country of Origin : | USA | ||||||||||||||||||||
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